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1

Epithelial cell plasticity defines heterogeneity in lung cancer

Sarode, Poonam, Mansouri, Siavash, Karger, Annika, Schaefer, Martina Barbara, Grimminger, Friedrich, Seeger, Werner, Savai, Rajkumar

Journal:

Cellular Signalling

Année:

2020

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2020

2

Riociguat dose titration in patients with chronic thromboembolic pulmonary hypertension (CTEPH) or pulmonary arterial hypertension (PAH)

Hossein A Ghofrani, Marius M Hoeper, Gert Hoeffken, Michael Halank, Gerrit Weimann, Friedrich Grimminger, the study group

Journal:

BMC Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 64 KB

english, 2009

3

Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond

Ghofrani, Hossein A., Osterloh, Ian H., Grimminger, Friedrich

Journal:

Nature Reviews Drug Discovery

Année:

2006

Langue:

english

Fichier:

PDF, 473 KB

english, 2006

4

Surfactant alteration and replacement in acute respiratory distress syndrome

Andreas Günther, Clemens Ruppert, Reinhold Schmidt, Philipp Markart, Friedrich Grimminger, Dieter Walmrath, Werner Seeger

Journal:

Respiratory Research

Année:

2001

Langue:

english

Fichier:

PDF, 620 KB

english, 2001

5

Mechanisms of disease: pulmonary arterial hypertension

Schermuly, Ralph T., Ghofrani, Hossein A., Wilkins, Martin R., Grimminger, Friedrich

Journal:

Nature Reviews Cardiology (formerly Nature Clinical Practice Cardiovascular Medicine)

Année:

2011

Langue:

english

Fichier:

PDF, 4.03 MB

english, 2011

6

Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension

Boehm, Mario, Arnold, Nadine, Braithwaite, Adam, Pickworth, Josephine, Lu, Changwu, Novoyatleva, Tatyana, Kiely, David G., Grimminger, Friedrich, Ghofrani, Hossein A., Weissmann, Norbert, Seeger, Wern

Journal:

BMC Pulmonary Medicine

Année:

2018

Langue:

english

Fichier:

PDF, 984 KB

english, 2018

7

Hochdruck in der Lunge

Prof. Dr. Hossein-Ardeschir Ghofrani, Prof. Dr. Dr. Friedrich Grimminger

Journal:

Année:

2011

Langue:

german

Fichier:

PDF, 542 KB

german, 2011

8

Expression of mucosa-related integrin αEβ7 on alveolar T cells in interstitial lung diseases

LOHMEYER, FRIEDRICH, GRIMMINGER, MAUS, TENTER, MORR, VELCOVSKY, SEEGER, ROSSEAU

Journal:

Clinical & Experimental Immunology

Année:

1999

Langue:

english

Fichier:

PDF, 168 KB

english, 1999

9

Diacylglycerol regulates acute hypoxic pulmonary vasoconstriction via TRPC6

Beate Fuchs, Markus Rupp, Hossein A Ghofrani, Ralph T Schermuly, Werner Seeger, Friedrich Grimminger, Thomas Gudermann, Alexander Dietrich, Norbert Weissmann

Journal:

Respiratory Research

Année:

2011

Langue:

english

Fichier:

PDF, 376 KB

english, 2011

10

Effects of riociguat in severe experimental pulmonary hypertension

Baktybek Kojonazarov, Michaela Lang, Norbert Weissmann, Friedrich Grimminger, Johannes-Peter Stasch, Werner Seeger, Ardeschir Hossein Ghofrani, Ralph Schermuly

Journal:

BMC Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 133 KB

english, 2011

11

The soluble guanylate cyclase stimulator riociguat ameliorates pulmonary hypertension induced by hypoxia and SU5416 in rats

Michaela Lang, Baktybek Kojonazarov, Norbert Weissmann, Friedrich Grimminger, Johannes-Peter Stasch, Werner Seeger, Ardeschir Hossein Ghofrani, Ralph Schermuly

Journal:

BMC Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 136 KB

english, 2011

12

Acute effects of phosphodiesterase 5 (PDE5) inhibition, ANP and NO on epididymal contractility are preserved despite chronic PDE5 exposure

Andrea Mietens, Caroline Feuerstacke, Sabine Tasch, Gerrit Eichner, Ralph Theo Schermuly, Friedrich Grimminger, Dieter Müller, Ralf Middendorff

Journal:

BMC Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 138 KB

english, 2011

13

Improvement of right heart structure and function by BAY 41-8543 in pulmonary artery banded mice

Wiebke Janssen, Yves Schymura, Astrid Wietelmann, Johannes-Peter Stasch, Himal Luitel, Norbert Weissmann, Ardeschir Hossein Ghofrani, Friedrich Grimminger, Thomas Braun, Werner Seeger, Ralph Theo Sche

Journal:

BMC Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 138 KB

english, 2011

14

Correction: Improvement of right heart structure and function by BAY41-8543 in pulmonary artery banded mice

Wiebke Janssen, Yves Schymura, Astrid Wietelmann, Johannes-Peter Stasch, Himal Luitel, Norbert Weissmann, Ardeschir Hossein Ghofrani, Friedrich Grimminger, Thomas Braun, Werner Seeger, Ralph Theo Sche

Journal:

BMC Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 78 KB

english, 2011

15

Activation of soluble guanylate cyclase reverses pulmonary vascular remodeling induced by hypoxia in mice

Rio Dumitrascu, Norbert Weissmann, Ardeschir Hossein Ghofrani, Knut Beuerlein, Harald Schmidt, Johannes-Peter Stasch, Markus Gnoth, Werner Seeger, Friedrich Grimminger, Ralph Theo Schermuly

Journal:

BMC Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 188 KB

english, 2005

16

The phosphodiesterase 5 inhibitor, sildenafil, further augments the compensatory upregulation of NO-cGMP signalling in hypoxic pulmonary hypertension

Mark Kirsch, Norbert Weissmann, Barbara Kemp-Harper, Friedrich Grimminger, Harald HHW Schmidt

Journal:

BMC Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 198 KB

english, 2005

17

Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension

Soni Pullamsetti, Ladislau Kiss, Ardeschir Hossein Ghofrani, Robert Voswinckel, Peter Haredza, Walter Klepetko, Clemens Aigner, Ludger Fink, Jai Prakash Muyal, Norbert Weissmann, Friedrich Grimminger,

Journal:

BMC Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 187 KB

english, 2005

18

Inhaled NO and the guanylate cyclase stimulator Bay 41-2272 in oleic acid induced acute lung injury in rabbits

Andreas Weidenbach, Johannes-Peter Stasch, Ardeschir Hossein Ghofrani, Norbert Weissmann, Friedrich Grimminger, Werner Seeger, Ralph Theo Schermuly

Journal:

BMC Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 196 KB

english, 2005

19

sGC activation in pulmonary hypertension

Ardeschir Ghofrani, Friedrich Grimminger

Journal:

BMC Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 185 KB

english, 2005

20

sGC stimulators in experimental pulmonary hypertension

Ralph Theo Schermuly, Ardeschir Hossein Ghofrani, Friedrich Grimminger

Journal:

BMC Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 179 KB

english, 2007

21

sGC activators and stimulators attenuate ischemia/reperfusion injury of the lung

Bakytbek Egemnazarov, Akylbek Sydykov, Ralph T Schermuly, Norbert Weissmann, Johannes-Peter Stasch, Werner Seeger, Friedrich Grimminger, Hossain A Ghofrani

Journal:

BMC Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 65 KB

english, 2009

22

Effects of phosphodiesterase 4 inhibition on bleomycin-induced pulmonary fibrosis in mice

Sergey Udalov, Rio Dumitrascu, Soni S Pullamsetti, Hamza M Al-tamari, Norbert Weissmann, Hossein A Ghofrani, Andreas Guenther, Robert Voswinckel, Werner Seeger, Friedrich Grimminger, Ralph T Schermuly

Journal:

BMC Pulmonary Medicine

Année:

2010

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2010

23

Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury

Rio Dumitrascu, Silke Koebrich, Eva Dony, Norbert Weissmann, Rajkumar Savai, Soni S Pullamsetti, Hossein A Ghofrani, Arun Samidurai, Horst Traupe, Werner Seeger, Friedrich Grimminger, Ralph T Schermul

Journal:

BMC Pulmonary Medicine

Année:

2008

Langue:

english

Fichier:

PDF, 3.09 MB

english, 2008

24

Proteinaceous bacterial toxins and pathogenesis of sepsis syndrome and septic shock: the unknown connection

Sucharit Bhakdi, Friedrich Grimminger, Norbert Suttorp, Dieter Walmrath, Werner Seeger

Journal:

Medical Microbiology and Immunology

Année:

1994

Langue:

english

Fichier:

PDF, 3.31 MB

english, 1994

25

Proteinaceous bacterial toxins and pathogenesis of sepsis syndrome and septic shock: the unknown connection

Sucharit Bhakdi, Friedrich Grimminger, Norbert Suttorp, Dieter Walmrath, Werner Seeger

Journal:

Medical Microbiology and Immunology

Année:

1994

Langue:

english

Fichier:

PDF, 693 KB

english, 1994

26

Neue Therapieoptionen in der Behandlung der pulmonalarteriellen Hypertonie

Hossein Ardeschir Ghofrani, Robert Voswinckel, Frank Reichenberger, Friedrich Grimminger, Werner Seeger

Journal:

Année:

2005

Fichier:

PDF, 327 KB

2005

27

HIV-assoziierte pulmonale Hypertonie

Georg Friese, Jürgen Lohmeyer, Werner Seeger, Friedrich Grimminger, Hossein Ardeschir Ghofrani

Journal:

Année:

2005

Fichier:

PDF, 259 KB

2005

28

ω-3 vs. ω-6 lipid emulsions exert differential influence on neutrophils in septic shock patients: impact on plasma fatty acids and lipid mediator generation

Konstantin Mayer, Christine Fegbeutel, Katja Hattar, Ulf Sibelius, Hans-Joachim Krämer, Kai-Uwe Heuer, Bettina Temmesfeld-Wollbrück, Stephanie Gokorsch, Friedrich Grimminger, Werner Seeger

Journal:

Intensive Care Medicine

Année:

2003

Langue:

english

Fichier:

PDF, 204 KB

english, 2003

29

Direct eicosanoid profiling of the hypoxic lung by comprehensive analysis via capillary liquid chromatography with dual online photodiode-array and tandem mass-spectrometric detection

Ladislau Kiss, Yasmin Röder, Jens Bier, Norbert Weissmann, Werner Seeger, Friedrich Grimminger

Journal:

Analytical and Bioanalytical Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 471 KB

english, 2008

30

Direct and simultaneous profiling of epoxyeicosatrienoic acid enantiomers by capillary tandem column chiral-phase liquid chromatography with dual online photodiode array and tandem mass spectrometric detection

Ladislau Kiss, Jens Bier, Yasmin Röder, Norbert Weissmann, Friedrich Grimminger, Werner Seeger

Journal:

Analytical and Bioanalytical Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 256 KB

english, 2008

31

Central sleep apnoea and unilateral diaphragmatic paralysis associated with vertebral artery compression of the medulla oblongata

Richard Schulz, Christine Fegbeutel, Andre Althoff, Horst Traupe, Friedrich Grimminger, Werner Seeger

Journal:

Journal of Neurology

Année:

2003

Langue:

english

Fichier:

PDF, 474 KB

english, 2003

32

Effect of 3 hours of passive smoke exposure in the evening on inflammatory markers in bronchoalveolar and nasal lavage fluid in subjects with mild asthma

Dennis Nowak, Rudolf Jörres, Lucia Martinez-Müller, Friedrich Grimminger, Werner Seeger, Frauke Koops, Helgo Magnussen

Journal:

International Archives of Occupational and Environmental Health

Année:

1997

Langue:

english

Fichier:

PDF, 200 KB

english, 1997

33

Real-time quantitative RT–PCR after laser-assisted cell picking

Fink, Ludger, Seeger, Werner, Ermert, Leander, Hänze, Jörg, Stahl, Ulrich, Grimminger, Friedrich, Kummer, Wolfgang, Bohle, Rainer M.

Journal:

Nature Medicine

Année:

1998

Langue:

english

Fichier:

PDF, 130 KB

english, 1998

34

Targeting non-malignant disorders with tyrosine kinase inhibitors

Grimminger, Friedrich, Schermuly, Ralph T., Ghofrani, Hossein A.

Journal:

Nature Reviews Drug Discovery

Année:

2010

Langue:

english

Fichier:

PDF, 536 KB

english, 2010

35

In vivo TRPC functions in the cardiopulmonary vasculature

Alexander Dietrich, Hermann Kalwa, Beate Fuchs, Friedrich Grimminger, Norbert Weissmann, Thomas Gudermann

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 940 KB

english, 2007

36

Increase in alveolar antioxidant levels in hyperoxic and anoxic ventilated rabbit lungs during ischemia

Reinhold Schmidt, Christoph Schäfer, Thomas Luboeinski, Alexander Löckinger, Gerd Hermle, Friedrich Grimminger, Werner Seeger, Ardeschir Ghofrani, Hartwig Schütte, Andreas Günther

Journal:

Free Radical Biology and Medicine

Année:

2004

Langue:

english

Fichier:

PDF, 363 KB

english, 2004

37

Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species

Parag Goyal, Norbert Weissmann, Friedrich Grimminger, Cornelia Hegel, Lucius Bader, Frank Rose, Ludger Fink, Hossein A Ghofrani, Ralph T Schermuly, Harald H.H.W Schmidt, Werner Seeger, Jörg Hänze

Journal:

Free Radical Biology and Medicine

Année:

2004

Langue:

english

Fichier:

PDF, 380 KB

english, 2004

38

Potential Role of NADPH Oxidase 1 Derived ROS in Vascular Remodeling in Monocrotaline-induced Pulmonary Arterial Hypertension of Rats

Florian Veit, Bakytbek Egemnazarov, Hossein Ardeschir Ghofrani, Ralph Theo Schermuly, Werner Seeger, Friedrich Grimminger, Norbert Weissmann

Journal:

Free Radical Biology and Medicine

Année:

2010

Langue:

english

Fichier:

PDF, 309 KB

english, 2010

39

Role of Reactive Oxygen Species in Acute Pulmonary Oxygen Sensing

Pak Oleg, Natascha Sommer, Hossein A. Ghofrani, Ralph T. Schermuly, Werner Seeger, Friedrich Grimminger, Norbert Weissmann

Journal:

Free Radical Biology and Medicine

Année:

2010

Langue:

english

Fichier:

PDF, 397 KB

english, 2010

40

Hypoxia induces Kv channel current inhibition by increased NADPH oxidase-derived reactive oxygen species

Manish Mittal, Xiang Q. Gu, Oleg Pak, Matthew E. Pamenter, Daniela Haag, D. Beate Fuchs, Ralph T. Schermuly, H.A. Ghofrani, Ralf P. Brandes, Werner Seeger, Friedrich Grimminger, Gabriel G. Haddad, Nor

Journal:

Free Radical Biology and Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2012

41

Phosphodiesterase 5 (PDE5) inhibition, ANP and NO rapidly reduce epididymal duct contractions, but long-term PDE5 inhibition in vivo does not

Andrea Mietens, Sabine Tasch, Caroline Feuerstacke, Gerrit Eichner, Johanna Volkmann, Ralph Theo Schermuly, Friedrich Grimminger, Dieter Müller, Ralf Middendorff

Journal:

Molecular and Cellular Endocrinology

Année:

2012

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2012

42

Redox signaling and reactive oxygen species in hypoxic pulmonary vasoconstriction

Beate Fuchs, Natascha Sommer, Alexander Dietrich, Ralph Theo Schermuly, Hossein Ardeschir Ghofrani, Friedrich Grimminger, Werner Seeger, Thomas Gudermann, Norbert Weissmann

Journal:

Respiratory Physiology & Neurobiology

Année:

2010

Langue:

english

Fichier:

PDF, 631 KB

english, 2010

43

Effects of arachidonic acid metabolism on hypoxic vasoconstriction in rabbit lungs

Norbert Weissmann, Werner Seeger, Jörg Conzen, Ladislau Kiss, Friedrich Grimminger

Journal:

European Journal of Pharmacology

Année:

1998

Langue:

english

Fichier:

PDF, 253 KB

english, 1998

44

Nebulization of biodegradable nanoparticles: impact of nebulizer technology and nanoparticle characteristics on aerosol features

Lea Ann Dailey, Thomas Schmehl, Tobias Gessler, Matthias Wittmar, Friedrich Grimminger, Werner Seeger, Thomas Kissel

Journal:

Journal of Controlled Release

Année:

2003

Langue:

english

Fichier:

PDF, 827 KB

english, 2003

45

Physiologic basis for the treatment of pulmonary hypertension

Horst Olschewski, Andrea Olschewski, Frank Rose, Ralph Schermuly, Hartwig Schütte, Norbert Weissmann, Werner Seeger, Friedrich Grimminger

Journal:

Journal of Laboratory and Clinical Medicine

Année:

2001

Langue:

english

Fichier:

PDF, 229 KB

english, 2001

46

Cellular pathophysiology and therapy of pulmonary hypertension

Horst Olschewski, Frank Rose, Ekkehard Grünig, H.Ardeschir Ghofrani, Dieter Walmrath, Richard Schulz, Ralph Schermuly, Friedrich Grimminger, Werner Seeger

Journal:

Journal of Laboratory and Clinical Medicine

Année:

2001

Langue:

english

Fichier:

PDF, 141 KB

english, 2001

47

Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction

Farzaneh Ketabchi, Hossein A Ghofrani, Ralph T Schermuly, Werner Seeger, Friedrich Grimminger, Bakytbek Egemnazarov, S Mostafa Shid-Moosavi, Gholam A Dehghani, Norbert Weissmann, Natascha Sommer

Journal:

Respiratory Research

Année:

2012

Langue:

english

Fichier:

PDF, 478 KB

english, 2012

48

Genomic Organization and Regulation of a Human 7-Helix Transmembrane Receptor Which Is Expressed in Pulmonary Epithelial Cells and Induced in Hypoxia

Jörg Hänze, David A. Groneberg, Frank Rose, Anika Hanisch, Jörg Dötsch, Christian Peiser, Werner Seeger, Wolfgang Rascher, Axel Fischer, Friedrich Grimminger

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 270 KB

english, 2002

49

Hydrogen Peroxide-Induced Increase in Lung Endothelial and Epithelial Permeability-Effect of Adenylate Cyclase Stimulation and Phosphodiesterase Inhibition

Werner Seeger, Tanja Hansen, Renate Rössig, Thomas Schmehl, Hartwig Schütte, Hans-Joachim Krämer, Dieter Walmrath, Norbert Weissmann, Friedrich Grimminger, Norbert Suttorp

Journal:

Microvascular Research

Année:

1995

Fichier:

PDF, 643 KB

1995

50

Hypoxic vasoconstriction in buffer-perfused rabbit lungs

Norbert Weissmann, Friedrich Grimminger, Dieter Walmrath, Werner Seeger

Journal:

Respiration Physiology

Année:

1995

Langue:

english

Fichier:

PDF, 741 KB

english, 1995